In recent internet surfing I came across a very scientific article, Molecular Switch Linking Infectious Disease And Depression Identified. The study came to some interesting and complicated conclusions--something about a link between the molecular changes in people with chronic inflammatory diseases and depression (I won't try to explain any more because I'm not sure I even really understood it). Apparently there are all sorts of implications for the next generation of antidepressant. But reading the article left me with one huge, nagging question:
How can you tell if a mouse if depressed?
See, the researchers did all their experimenting on mice and their conclusions are based on observed behavior in the mice. So I'm just wondering how can they tell? And, really, how many other treatments are based on interpretations of mouse behavior?
Oh, that's right! Almost all of them. (For proof read here, here, here, and here!)
But don't worry, researchers have also found that ever-happy mice may hold the key to new treatment of depression.
Somehow, I'm not convinced.